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Eltoprazine dihydrochloride

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Purity:99.94%

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COA HNMR HPLC

Eltoprazine dihydrochloride

Catalog No. T7746Cas No. 143485-51-2

Eltoprazine dihydrochloride is a drug that had previously been developed for aggression, has recently been investigated for L-DOPA-induced dyskinesia in animal models of Parkinson′s disease (PD) and in dyskinetic PD patients.

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Pack Size	Price	Availability
5 mg	$48	In Stock
10 mg	$71	In Stock
25 mg	$127	In Stock
50 mg	$191	In Stock
100 mg	$288	In Stock
1 mL x 10 mM (in DMSO)	$63	In Stock

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Product Introduction

Bioactivity

Description	Eltoprazine dihydrochloride is a drug that had previously been developed for aggression, has recently been investigated for L-DOPA-induced dyskinesia in animal models of Parkinson´s disease (PD) and in dyskinetic PD patients.
In vitro	In the elevated plus maze eltoprazine increased anxiety?like behavior.?On the other hand, it induced a clear?cut anxiolytic effect in context fear conditioning test starting at ca. 0.3 mg/kg[1]

Chemical Properties

Molecular Weight	293.19
Formula	C12H18Cl2N2O2
Cas No.	143485-51-2

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 10 mg/mL (34.11 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.4108 mL	17.0538 mL	34.1076 mL	170.5379 mL
5 mM	0.6822 mL	3.4108 mL	6.8215 mL	34.1076 mL
10 mM	0.3411 mL	1.7054 mL	3.4108 mL	17.0538 mL
20 mM	0.1705 mL	0.8527 mL	1.7054 mL	8.5269 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

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